Follow-up of a Patient With Chronic Hepatitis C–associated Cryoglobulinemia During Four and a Half Years of Maintenance Interferon Treatment

In this report, we present a patient with chronic hepatitis C–associated cryoglobulinemia who was kept on maintenance interferon treatment because of flare-ups in cryoglobulinemia-associated signs and hepatitis after withdrawal, dose reduction, and increase in dose intervals of interferon. This type of interferon use for treatment of cryoglobulinemia gave us a chance to observe the long-term effects of interferon on cryoglobulinemia and chronic hepatitis C remission for biochemical, virologic, and histologic aspects.