Peptide-membrane interactions and a new principle in quantitative structure-activity relationships

Ideas about “active conformations” of peptides as the basis of their biological action are reviewed and put into perspective with recent work on the possible role of the lipid phase of the target cell membrane in mediating receptor subtype selectivity.

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Veröffentlicht in:	Biopolymers 1991-05, Vol.31 (6), p.785-792
1. Verfasser:	Schwyzer, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Biological and medical sciences Cell Membrane Fundamental and applied biological sciences. Psychology Molecular biophysics Molecular Sequence Data Peptides - chemistry Peptides - pharmacology plasma membranes Protein Conformation Receptors, Cell Surface reviews Structure-Activity Relationship
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description	Ideas about “active conformations” of peptides as the basis of their biological action are reviewed and put into perspective with recent work on the possible role of the lipid phase of the target cell membrane in mediating receptor subtype selectivity.
doi_str_mv	10.1002/bip.360310624
format	Article
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subjects	Amino Acid Sequence Biological and medical sciences Cell Membrane Fundamental and applied biological sciences. Psychology Molecular biophysics Molecular Sequence Data Peptides - chemistry Peptides - pharmacology plasma membranes Protein Conformation Receptors, Cell Surface reviews Structure-Activity Relationship
title	Peptide-membrane interactions and a new principle in quantitative structure-activity relationships
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