Peptide-membrane interactions and a new principle in quantitative structure-activity relationships

Peptide-membrane interactions and a new principle in quantitative structure-activity relationships

Ideas about “active conformations” of peptides as the basis of their biological action are reviewed and put into perspective with recent work on the possible role of the lipid phase of the target cell membrane in mediating receptor subtype selectivity.

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Bibliographische Detailangaben
Veröffentlicht in:Biopolymers 1991-05, Vol.31 (6), p.785-792
1. Verfasser: Schwyzer, Robert
Format: Artikel
Sprache:eng
Schlagworte:
Amino Acid Sequence
Biological and medical sciences
Cell Membrane
Fundamental and applied biological sciences. Psychology
Molecular biophysics
Molecular Sequence Data
Peptides - chemistry
Peptides - pharmacology
plasma membranes
Protein Conformation
Receptors, Cell Surface
reviews
Structure-Activity Relationship
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Beschreibung
Zusammenfassung:Ideas about “active conformations” of peptides as the basis of their biological action are reviewed and put into perspective with recent work on the possible role of the lipid phase of the target cell membrane in mediating receptor subtype selectivity.
ISSN:0006-3525
1097-0282
DOI:10.1002/bip.360310624