Enantioselective Catalysis Using Heterogeneous Bis(oxazoline) Ligands:  Which Factors Influence the Enantioselectivity?

Chiral bis(oxazoline) (BOX) ligands have been successfully used in the asymmetric catalysis of a variety of reactions for the past decade. Rechavi and Lemaire present different methods of heterogenization that have been developed for the separation and recycling of BOX ligands. The various methods include immobilization by covalent or noncovalent bonding, on organic or on inorganic supports, and using soluble or insoluble polymers.