The role of forced swim test on neutrophil leukocytosis observed during inflammation induced by LPS in rodents

Adult male rats were administered intrapleural (ipl) or intraperitoneal (ip) injection of lipopolysaccharide (LPS), 24 h after being submitted to forced swim test (FST). Four hours after LPS challenge, an increase in pleural and peritoneal leukocyte and neutrophil counts in animals not exposed to FS...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Progress in neuro-psychopharmacology & biological psychiatry 2002-06, Vol.26 (5), p.891-895
Hauptverfasser:	Altenburg, Sonia P., Ventura, Diana G., Da-Silva, Vilma A., Malheiros, Luciana R., Castro-Faria-Neto, Hugo C., Bozza, Patrı&#x0301, cia T., Teixeira, Nancy A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult and adolescent clinical studies Animals Ascitic Fluid - pathology Behavioral psychophysiology Biological and medical sciences Depression Depression - immunology Depression - psychology Forced swim test Fundamental and applied biological sciences. Psychology Immunology and behavior Inflammation Inflammation - immunology Inflammation - psychology Injections, Intraperitoneal Leukocyte Count - methods Leukocytosis - immunology Leukocytosis - pathology Leukocytosis - psychology Lipopolysaccharides - administration & dosage LPS Male Medical sciences Mood disorders Neutrophils Neutrophils - drug effects Neutrophils - immunology Neutrophils - pathology Pleura - pathology Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Psychopathology. Psychiatry Rats Rats, Wistar Rodent Swimming - physiology Swimming - psychology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Adult male rats were administered intrapleural (ipl) or intraperitoneal (ip) injection of lipopolysaccharide (LPS), 24 h after being submitted to forced swim test (FST). Four hours after LPS challenge, an increase in pleural and peritoneal leukocyte and neutrophil counts in animals not exposed to FST was noted. FST induced a marked increase in pleural, but not in peritoneal, neutrophil leukocytosis. The results suggest that lowered mood may increase inflammatory response to LPS.
ISSN:	0278-5846 1878-4216
DOI:	10.1016/S0278-5846(01)00335-9