A novel principle for assessment of stimulated fibrinolysis

After venous occlusion (VO), D-dimer levels were measured by means of an ELISA technique, in citrated plasma clotted by thrombin and in serum from whole blood. D-dimer levels increased with duration of incubation (30 min to 24 hours). D-dimer values, both in clotted plasma and in serum (n=12), incub...

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Veröffentlicht in:	Thrombosis research 1991-06, Vol.62 (6), p.725-735
Hauptverfasser:	Haaland, A.K., Skjønsberg, O.H., Varet, A., Ruyter, R., Godal, H.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Biological and medical sciences Blood coagulation Constriction D-dimer Enzyme-Linked Immunosorbent Assay Female Fibrin Fibrinogen Degradation Products - analysis Fibrinolysis Humans Investigative techniques, diagnostic techniques (general aspects) Latex Fixation Tests Male Medical sciences Middle Aged Thrombophlebitis - blood Thrombophlebitis - drug therapy Tissue Plasminogen Activator - analysis Veins venous occlusion Warfarin - therapeutic use
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Zusammenfassung:	After venous occlusion (VO), D-dimer levels were measured by means of an ELISA technique, in citrated plasma clotted by thrombin and in serum from whole blood. D-dimer levels increased with duration of incubation (30 min to 24 hours). D-dimer values, both in clotted plasma and in serum (n=12), incubated 4 hours at room temperature, correlated well with euglobulin clot lysis time (ECLT)(r= -0.85 and -0.89, respectively, p
ISSN:	0049-3848 1879-2472
DOI:	10.1016/0049-3848(91)90376-8