Randomized Controlled Trial of Fluticasone in Preschool Children with Intermittent Wheeze

Preschool children with intermittent wheeze are often prescribed inhaled corticosteroids, although there is no proven benefit. Measurement of airway resistance by the interrupter technique can be used to objectively assess response to treatment. If lung function improves, treatment may be justified....

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2002-10, Vol.166 (7), p.945-949
Hauptverfasser:	Pao, Caroline S, McKenzie, Sheila A
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Airway Resistance - drug effects Androstadienes - therapeutic use Anti-Inflammatory Agents - therapeutic use Biological and medical sciences Bronchoconstriction - drug effects Child Welfare Child, Preschool Cross-Over Studies Double-Blind Method Female Fluticasone Glucocorticoids Humans Immunoglobulin E - blood Lung - blood supply Lung - drug effects Lung - physiology Male Medical sciences Multivariate Analysis Pharmacology. Drug treatments Respiratory Hypersensitivity - drug therapy Respiratory Sounds - drug effects Respiratory system Skin Tests Time Factors Treatment Outcome
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Beschreibung
Zusammenfassung:	Preschool children with intermittent wheeze are often prescribed inhaled corticosteroids, although there is no proven benefit. Measurement of airway resistance by the interrupter technique can be used to objectively assess response to treatment. If lung function improves, treatment may be justified. Children with intermittent wheeze aged 2 to
ISSN:	1073-449X 1535-4970
DOI:	10.1164/rccm.200203-265OC