Gene therapy gets the Beauty treatment

Gene therapy gets the Beauty treatment

Gene-deleted adenovirus vectors modified to carry the Sleeping Beauty transposon machinery achieve long-term transgene stabilization and expression.

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Bibliographische Detailangaben
Veröffentlicht in:Nature biotechnology 2002-10, Vol.20 (10), p.987-988
1. Verfasser: Linden, R. Michael
Format: Artikel
Sprache:eng
Schlagworte:
Adenoviridae - genetics
Agriculture
Animals
Bioinformatics
Biomedical and Life Sciences
Biomedical Engineering/Biotechnology
Biomedicine
Biotechnology
DNA Transposable Elements - genetics
DNA-Binding Proteins - genetics
Gene Expression Regulation
Gene Transfer Techniques
Genetic Therapy - methods
HeLa Cells
Humans
Life Sciences
Liver - enzymology
Mice
Mice, Inbred C57BL
news-and-views
Transgenes - genetics
Transposases - classification
Transposases - genetics
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Beschreibung
Zusammenfassung:Gene-deleted adenovirus vectors modified to carry the Sleeping Beauty transposon machinery achieve long-term transgene stabilization and expression.
ISSN:1087-0156
1546-1696
DOI:10.1038/nbt1002-987