Endocarditis Caused by Methicillin-Resistant Staphylococcus aureus: Treatment Failure with Linezolid

We describe 2 cases of endocarditis caused by methicillin-resistant Staphylococcus aureus that failed to respond to intravenous linezolid therapy but were successfully treated with trimethoprim-sulfamethoxazole plus gentamicin and vancomycin plus rifampin.

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Bibliographische Detailangaben
Veröffentlicht in:	Clinical infectious diseases 2002-10, Vol.35 (8), p.1018-1020
Hauptverfasser:	Ruiz, Maria E., Guerrero, Isabel C., Tuazon, Carmelita U.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetamides - therapeutic use Aged Anti-Bacterial Agents - therapeutic use Bacteremia Bacterial diseases Biological and medical sciences Blood Brief Report Cardiology. Vascular system Catheters Cultural groups Dosage Endocardial and cardiac valvular diseases Endocarditis Endocarditis, Bacterial - drug therapy Heart Heart valves Hospital admissions Human bacterial diseases Humans Infections Infectious diseases Linezolid Medical sciences Methicillin Resistance - physiology Oxazolidinones - therapeutic use Staphylococcal Infections - drug therapy Staphylococcal infections, streptococcal infections, pneumococcal infections Staphylococcus aureus Staphylococcus aureus - drug effects Treatment Failure
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Beschreibung
Zusammenfassung:	We describe 2 cases of endocarditis caused by methicillin-resistant Staphylococcus aureus that failed to respond to intravenous linezolid therapy but were successfully treated with trimethoprim-sulfamethoxazole plus gentamicin and vancomycin plus rifampin.
ISSN:	1058-4838 1537-6591
DOI:	10.1086/342698