Atorvastatin Reduces Plasma Levels of Factor VII Activity and Factor VII Antigen in Patients with Hyperlipidemia

Atorvastatin is a powerful new synthetic 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor currently in clinical use. Its effects on plasma levels of factor VII were examined in 30 hyperlipidemic patients. After 12 weeks of atorvastatin treatment, factor VII activity (FVIIc) and factor VII a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of Atherosclerosis and Thrombosis 2002, Vol.9(1), pp.72-77
Hauptverfasser:	Morishita, Eriko, Minami, Shinji, Ishino, Chizuko, Kanno, Masanori, Uotani, Chika, Asakura, Hidesaku, Matsuda, Tamotsu, Nakao, Shinji
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anticholesteremic Agents - administration & dosage Antigens - metabolism Atorvastatin Blood Glucose Factor VII Factor VII - metabolism Female Fibrinogen - metabolism Hemostasis - drug effects Heptanoic Acids - administration & dosage Humans Hyperlipidemia Hyperlipidemias - drug therapy Hyperlipidemias - epidemiology Hyperlipidemias - metabolism Isoantigens - blood Male Middle Aged Pyrroles - administration & dosage Risk Factors Thrombosis - epidemiology Thrombosis - prevention & control Triglyceride Triglycerides - blood
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Atorvastatin is a powerful new synthetic 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor currently in clinical use. Its effects on plasma levels of factor VII were examined in 30 hyperlipidemic patients. After 12 weeks of atorvastatin treatment, factor VII activity (FVIIc) and factor VII antigen (FVIIag) levels had decreased by 13% (p
ISSN:	1340-3478 1880-3873
DOI:	10.5551/jat.9.72