Central precocious puberty in girls with Williams syndrome

Central precocious puberty in girls with Williams syndrome

We report an estimated prevalence of precocious puberty of 1 in 5 to 6 girls with Williams syndrome (18.3%). Mean menarcheal age of 86 girls with Williams syndrome was 11.5 ± 1.7 (±SD) years. Distribution of menarcheal age was significantly different from that in normal girls (12.9 ± 1.1 years;n = 7...

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Veröffentlicht in:The Journal of pediatrics 2002-09, Vol.141 (3), p.441-444
Hauptverfasser: Partsch, Carl-Joachim, Japing, Insa, Siebert, Reiner, Gosch, Angela, Wessel, Armin, Sippell, Wolfgang G., Pankau, Rainer
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Age Distribution
Biological and medical sciences
Case-Control Studies
Child
Female
Female genital diseases
Germany - epidemiology
Gynecology. Andrology. Obstetrics
Humans
Medical sciences
Non tumoral diseases
Prevalence
Puberty, Precocious - epidemiology
Puberty, Precocious - etiology
Statistics, Nonparametric
Williams Syndrome - complications
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Zusammenfassung:We report an estimated prevalence of precocious puberty of 1 in 5 to 6 girls with Williams syndrome (18.3%). Mean menarcheal age of 86 girls with Williams syndrome was 11.5 ± 1.7 (±SD) years. Distribution of menarcheal age was significantly different from that in normal girls (12.9 ± 1.1 years;n = 759). (J Pediatr 2002;141:441-4)
ISSN:0022-3476
1097-6833
DOI:10.1067/mpd.2002.127280