Velo‐cardio‐facial syndrome: Clinical report of a 70‐year‐old woman

A clinical report is presented of a 70‐year‐old female in whom, after more than 40 years residential psychiatric care, the diagnosis of velo‐cardio‐facial syndrome (VCFS) was ultimately established; the patient has a 46, XX.ish del (22)(q11.2q11.2)(D22S75‐) karyotype. It is advocated that a rather specific psychopathological profile is present in patients with VCFS, for which the term psychopathological phenotype is introduced, that should include data from genetics, neuropathology, development, psychology, and psychiatry. © 2002 Wiley‐Liss, Inc.