Enantioselective Synthesis of and with Allenes
A breakthrough in the catalytic enantioselective synthesis of allenes was recently reported by Hayashi and co‐workers: chiral trichlorosilyl allenes were generated with up to 90 % ee by palladium‐catalyzed hydrosilylation of but‐1‐en‐3‐ynes in the presence of a chiral ferrocenyl phosphane [Eq. (1)]....
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| Veröffentlicht in: | Angewandte Chemie International Edition 2002-08, Vol.41 (16), p.2933-2935 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | A breakthrough in the catalytic enantioselective synthesis of allenes was recently reported by Hayashi and co‐workers: chiral trichlorosilyl allenes were generated with up to 90 % ee by palladium‐catalyzed hydrosilylation of but‐1‐en‐3‐ynes in the presence of a chiral ferrocenyl phosphane [Eq. (1)]. This transformation, as well as further recent highlights in enantioselective allene synthesis, are summarized in this account. |
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| ISSN: | 1433-7851 1521-3773 |
| DOI: | 10.1002/1521-3773(20020816)41:16<2933::AID-ANIE2933>3.0.CO;2-6 |