Catalytic Beacons for the Detection of DNA and Telomerase Activity

DNA and telomerase activity are detected by a DNAzyme generated upon hybridization and opening of a functional catalytic beacon.

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Veröffentlicht in:Journal of the American Chemical Society 2004-06, Vol.126 (24), p.7430-7431
Hauptverfasser: Xiao, Yi, Pavlov, Valeri, Niazov, Tamara, Dishon, Arnon, Kotler, Moshe, Willner, Itamar
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container_end_page 7431
container_issue 24
container_start_page 7430
container_title Journal of the American Chemical Society
container_volume 126
creator Xiao, Yi
Pavlov, Valeri
Niazov, Tamara
Dishon, Arnon
Kotler, Moshe
Willner, Itamar
description DNA and telomerase activity are detected by a DNAzyme generated upon hybridization and opening of a functional catalytic beacon.
doi_str_mv 10.1021/ja031875r
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subjects Biological and medical sciences
Biosensors
Biotechnology
Catalysis
Cell Count
DNA - analysis
DNA - metabolism
DNA, Catalytic - chemistry
DNA, Catalytic - metabolism
Enzyme Activation
Fundamental and applied biological sciences. Psychology
HeLa Cells
Humans
Methods. Procedures. Technologies
Molecular Probe Techniques
Nucleic Acid Conformation
Nucleic Acid Hybridization
Nucleic Acids - chemistry
Photochemistry
Sensitivity and Specificity
Telomerase - analysis
Telomerase - chemistry
Telomerase - metabolism
Time Factors
Various methods and equipments
title Catalytic Beacons for the Detection of DNA and Telomerase Activity
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