Catalytic Beacons for the Detection of DNA and Telomerase Activity

DNA and telomerase activity are detected by a DNAzyme generated upon hybridization and opening of a functional catalytic beacon.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of the American Chemical Society 2004-06, Vol.126 (24), p.7430-7431
Hauptverfasser:	Xiao, Yi, Pavlov, Valeri, Niazov, Tamara, Dishon, Arnon, Kotler, Moshe, Willner, Itamar
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biosensors Biotechnology Catalysis Cell Count DNA - analysis DNA - metabolism DNA, Catalytic - chemistry DNA, Catalytic - metabolism Enzyme Activation Fundamental and applied biological sciences. Psychology HeLa Cells Humans Methods. Procedures. Technologies Molecular Probe Techniques Nucleic Acid Conformation Nucleic Acid Hybridization Nucleic Acids - chemistry Photochemistry Sensitivity and Specificity Telomerase - analysis Telomerase - chemistry Telomerase - metabolism Time Factors Various methods and equipments
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Beschreibung
Zusammenfassung:	DNA and telomerase activity are detected by a DNAzyme generated upon hybridization and opening of a functional catalytic beacon.
ISSN:	0002-7863 1520-5126
DOI:	10.1021/ja031875r