A New Cycloamphilectene Metabolite from the Vanuatu Sponge Axinella sp

A New Cycloamphilectene Metabolite from the Vanuatu Sponge Axinella sp

A new diterpene, N-formyl-7-amino-11-cycloamphilectene (1), was isolated from the apolar extract of the Vanuatu sponge Axinella sp. The structure and relative stereochemistry were established by spectroscopic and single-crystal X-ray studies.

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Bibliographische Detailangaben
Veröffentlicht in:Journal of natural products (Washington, D.C.) D.C.), 2002-08, Vol.65 (8), p.1210-1212
Hauptverfasser: Ciasullo, L, Cutignano, A, Casapullo, A, Puliti, R, Mattia, C. A, Debitus, C, Riccio, R, Gomez-Paloma, L
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Axinella
Biological and medical sciences
Chromatography, High Pressure Liquid
Crystallography, X-Ray
cycloamphilectenes
diterpenes
Diterpenes - chemistry
Diterpenes - isolation & purification
General pharmacology
Marine
Medical sciences
Molecular Conformation
Molecular Structure
natural products
Nuclear Magnetic Resonance, Biomolecular
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Porifera - chemistry
Stereoisomerism
Vanuatu
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Zusammenfassung:A new diterpene, N-formyl-7-amino-11-cycloamphilectene (1), was isolated from the apolar extract of the Vanuatu sponge Axinella sp. The structure and relative stereochemistry were established by spectroscopic and single-crystal X-ray studies.
ISSN:0163-3864
1520-6025
DOI:10.1021/np010666m