Partial lesion of thalamic ventral intermediate nucleus after chronic high-frequency stimulation

A 73‐year‐old man with Parkinson's disease underwent thalamic stimulation for disabling tremor with excellent results only when stimulation on. Post‐mortem neuropathology (7 years postoperatively) revealed 60% cell loss within 0.5 mm of the electrode tip. Tremor improvement was attributable to...

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Veröffentlicht in:	Movement disorders 2004-06, Vol.19 (6), p.709-711
Hauptverfasser:	Henderson, Jasmine, Rodriguez, Michael, O'Sullivan, Dudley, Pell, Malcolm, Fung, Victor, Benabid, Alim Louis, Halliday, Glenda
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Electric Stimulation - instrumentation Humans Male Medical sciences Middle Aged Neurology Parkinson Disease - complications Parkinson Disease - pathology Parkinson Disease - therapy Parkinson's disease Radio Waves Ventral Thalamic Nuclei - pathology VIM stimulation
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Zusammenfassung:	A 73‐year‐old man with Parkinson's disease underwent thalamic stimulation for disabling tremor with excellent results only when stimulation on. Post‐mortem neuropathology (7 years postoperatively) revealed 60% cell loss within 0.5 mm of the electrode tip. Tremor improvement was attributable to chronic stimulation, not microthalamotomy. © 2004 Movement Disorder Society
ISSN:	0885-3185 1531-8257
DOI:	10.1002/mds.10709