Mitral annular calcification is associated with osteoporosis in women

Few studies have suggested association between mitral annular calcification (MAC) and osteoporosis in women who are post-menopausal . However, the association of MAC with osteoporosis in women, in relation to bone resorption, as assessed by using the dual-energy x-ray absorptiometry method (DEXA), have not been performed. We sought to examine the association between MAC and osteoporosis. In this prospective, observational study carried out in a tertiary referral center, 340 women (mean age ± SD, 56 ± 10 years; age range, 33–85 years) underwent echocardiography, with specific assesment of MAC and bone mineral density measurement (T-scores) using DEXA. MAC was absent in 123 patients (group I) and present in 217 patients (group II). Compared with the control group, the group with MAC had a significantly higher prevalence and severity of osteoporosis (18.2% vs 55.5%, P