Synthesis and application in asymmetric C-C bond formation of solution phase ligand libraries of monodentate phosphoramidites

A library of 96 unique monodentate phosphoramidite ligands has been synthesized in solution and used in the asymmetric conjugate addition of potassium vinyltrifluoroborate to enones resulting in up to 88% ee.

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Veröffentlicht in:Organic & biomolecular chemistry 2004-06, Vol.2 (12), p.1682-1684
Hauptverfasser: Duursma, Ate, Lefort, Laurent, Boogers, Jeroen A F, de Vries, André H M, de Vries, Johannes G, Minnaard, Adriaan J, Feringa, Ben L
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container_end_page 1684
container_issue 12
container_start_page 1682
container_title Organic & biomolecular chemistry
container_volume 2
creator Duursma, Ate
Lefort, Laurent
Boogers, Jeroen A F
de Vries, André H M
de Vries, Johannes G
Minnaard, Adriaan J
Feringa, Ben L
description A library of 96 unique monodentate phosphoramidite ligands has been synthesized in solution and used in the asymmetric conjugate addition of potassium vinyltrifluoroborate to enones resulting in up to 88% ee.
doi_str_mv 10.1039/b404996a
format Article
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source Royal Society of Chemistry Journals Archive (1841-2007); Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
title Synthesis and application in asymmetric C-C bond formation of solution phase ligand libraries of monodentate phosphoramidites
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