Autoantibody in a patient with chronic hepatitis C virus infection showing complete remission after interferon therapy
A 42‐year‐old woman was admitted to Kinashi Ohbayashi Hospital for liver dysfunction. She presented with hepatitis C viral infection accompanied by autoimmune hepatitis‐like serological manifestations, such as antinuclear antibody (ANA), antismooth muscle cell antibody and especially anti‐ribonucleo...
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| Veröffentlicht in: | Journal of gastroenterology and hepatology 2002-08, Vol.17 (8), p.925-928 |
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| container_issue | 8 |
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| container_title | Journal of gastroenterology and hepatology |
| container_volume | 17 |
| creator | AKASHI, YOSHIHIRO INOH, MASAYUKI SETO, KUNIO GAMO, NAOYUKI KUBOKI, MAKOTO KURATA, NORIYUKI |
| description | A 42‐year‐old woman was admitted to Kinashi Ohbayashi Hospital for liver dysfunction. She presented with hepatitis C viral infection accompanied by autoimmune hepatitis‐like serological manifestations, such as antinuclear antibody (ANA), antismooth muscle cell antibody and especially anti‐ribonucleoprotein (RNP) antibody and anti‐SSB antibody. After interferon therapy, hepatitis C virus was not detected and ANA, anti‐RNP antibody and anti‐SSB antibody disappeared. To our knowledge, this is the first reported hepatitis C patient showing anti‐RNP antibody and anti‐SSB antibody, having complete remission after interferon therapy. |
| doi_str_mv | 10.1046/j.1440-1746.2002.02651.x |
| format | Article |
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She presented with hepatitis C viral infection accompanied by autoimmune hepatitis‐like serological manifestations, such as antinuclear antibody (ANA), antismooth muscle cell antibody and especially anti‐ribonucleoprotein (RNP) antibody and anti‐SSB antibody. After interferon therapy, hepatitis C virus was not detected and ANA, anti‐RNP antibody and anti‐SSB antibody disappeared. 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To our knowledge, this is the first reported hepatitis C patient showing anti‐RNP antibody and anti‐SSB antibody, having complete remission after interferon therapy.</description><subject>Adult</subject><subject>Antiviral Agents - therapeutic use</subject><subject>anti‐RNP antibody</subject><subject>anti‐SSB antibody</subject><subject>Autoantibodies - blood</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>hepatitis C</subject><subject>Hepatitis C, Chronic - blood</subject><subject>Hepatitis C, Chronic - drug therapy</subject><subject>Hepatitis C, Chronic - pathology</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Interferon-alpha - therapeutic use</subject><subject>lupus‐like syndrome</subject><subject>Medical sciences</subject><subject>Remission Induction</subject><subject>Viral diseases</subject><subject>Viral hepatitis</subject><issn>0815-9319</issn><issn>1440-1746</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkEtv1DAQgC0EokvhLyBf4JbgsfOwDxyqVWlBlbj0bjneMfEqGwfb6Xb_PQm7olcuHmvmm4c-QiiwEljVfNmXUFWsgLZqSs4YLxlvaiifX5HNv8JrsmES6kIJUFfkXUp7xljF2votuQIOTaVa2JCnmzkHM2bfhd2J-pEaOpnsccz06HNPbR_D6C3tcU1nn-iWPvk4p4V1aLMPI019OPrxF7XhMA2YkUY8-JTWknEZ44Iur8NlEs09RjOd3pM3zgwJP1ziNXn8dvu4vS8eft593948FFaoGgpuhGts11nOO7djBjqHoDhII7FyqKSFWhqFleBM7hgKbhlI4A1vjGyduCafz2OnGH7PmLJeDrM4DGbEMCfdglKykfUCyjNoY0gpotNT9AcTTxqYXpXrvV7N6tWsXpXrv8r189L68bJj7g64e2m8OF6ATxfAJGsGF81ofXrhhAIhRLNwX8_c0Q94-u8D9I-7-_Un_gBRuJ8Z</recordid><startdate>200208</startdate><enddate>200208</enddate><creator>AKASHI, YOSHIHIRO</creator><creator>INOH, MASAYUKI</creator><creator>SETO, KUNIO</creator><creator>GAMO, NAOYUKI</creator><creator>KUBOKI, MAKOTO</creator><creator>KURATA, NORIYUKI</creator><general>Blackwell Science Pty</general><general>Blackwell Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200208</creationdate><title>Autoantibody in a patient with chronic hepatitis C virus infection showing complete remission after interferon therapy</title><author>AKASHI, YOSHIHIRO ; INOH, MASAYUKI ; SETO, KUNIO ; GAMO, NAOYUKI ; KUBOKI, MAKOTO ; KURATA, NORIYUKI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3951-2a3f6cbbc22bfd0a1bfe19218a8e4fe98c158a9e43208d0e32c01812626a87f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adult</topic><topic>Antiviral Agents - therapeutic use</topic><topic>anti‐RNP antibody</topic><topic>anti‐SSB antibody</topic><topic>Autoantibodies - blood</topic><topic>Biological and medical sciences</topic><topic>Female</topic><topic>hepatitis C</topic><topic>Hepatitis C, Chronic - blood</topic><topic>Hepatitis C, Chronic - drug therapy</topic><topic>Hepatitis C, Chronic - pathology</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Interferon-alpha - therapeutic use</topic><topic>lupus‐like syndrome</topic><topic>Medical sciences</topic><topic>Remission Induction</topic><topic>Viral diseases</topic><topic>Viral hepatitis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>AKASHI, YOSHIHIRO</creatorcontrib><creatorcontrib>INOH, MASAYUKI</creatorcontrib><creatorcontrib>SETO, KUNIO</creatorcontrib><creatorcontrib>GAMO, NAOYUKI</creatorcontrib><creatorcontrib>KUBOKI, MAKOTO</creatorcontrib><creatorcontrib>KURATA, NORIYUKI</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of gastroenterology and hepatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>AKASHI, YOSHIHIRO</au><au>INOH, MASAYUKI</au><au>SETO, KUNIO</au><au>GAMO, NAOYUKI</au><au>KUBOKI, MAKOTO</au><au>KURATA, NORIYUKI</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Autoantibody in a patient with chronic hepatitis C virus infection showing complete remission after interferon therapy</atitle><jtitle>Journal of gastroenterology and hepatology</jtitle><addtitle>J Gastroenterol Hepatol</addtitle><date>2002-08</date><risdate>2002</risdate><volume>17</volume><issue>8</issue><spage>925</spage><epage>928</epage><pages>925-928</pages><issn>0815-9319</issn><eissn>1440-1746</eissn><abstract>A 42‐year‐old woman was admitted to Kinashi Ohbayashi Hospital for liver dysfunction. 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| ispartof | Journal of gastroenterology and hepatology, 2002-08, Vol.17 (8), p.925-928 |
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| language | eng |
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| source | MEDLINE; Wiley Online Library All Journals |
| subjects | Adult Antiviral Agents - therapeutic use anti‐RNP antibody anti‐SSB antibody Autoantibodies - blood Biological and medical sciences Female hepatitis C Hepatitis C, Chronic - blood Hepatitis C, Chronic - drug therapy Hepatitis C, Chronic - pathology Human viral diseases Humans Infectious diseases Interferon-alpha - therapeutic use lupus‐like syndrome Medical sciences Remission Induction Viral diseases Viral hepatitis |
| title | Autoantibody in a patient with chronic hepatitis C virus infection showing complete remission after interferon therapy |
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