Synthesis of taurospongin A: a potent inhibitor of DNA polymerase and HIV reverse transcriptase, using pi-allyltricarbonyliron lactone complexes
The synthesis of taurospongin A has been achieved using, as a key step, a pi-allyltricarbonyliron lactone complex to control a highly stereoselective addition of a methyl group to a carbonyl unit located in the side chain of the complex.
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2002-08 (15), p.1624-1625 |
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| container_end_page | 1625 |
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| container_issue | 15 |
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| container_title | Chemical communications (Cambridge, England) |
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| creator | Hollowood, Christopher J Ley, Steven V Yamanoi, Shigeo |
| description | The synthesis of taurospongin A has been achieved using, as a key step, a pi-allyltricarbonyliron lactone complex to control a highly stereoselective addition of a methyl group to a carbonyl unit located in the side chain of the complex. |
| doi_str_mv | 10.1039/b204994p |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2002-08 (15), p.1624-1625 |
| issn | 1359-7345 1364-548X |
| language | eng |
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| source | MEDLINE; Royal Society of Chemistry Journals Archive (1841-2007); Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Alkynes - chemical synthesis Animals Enzyme Inhibitors - chemical synthesis Esters - chemical synthesis Indicators and Reagents Iron Compounds Lactones Magnetic Resonance Spectroscopy Nucleic Acid Synthesis Inhibitors Porifera - chemistry Reverse Transcriptase Inhibitors - chemical synthesis |
| title | Synthesis of taurospongin A: a potent inhibitor of DNA polymerase and HIV reverse transcriptase, using pi-allyltricarbonyliron lactone complexes |
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