Efficient, “Tin-Free” Radical Cyclization to Aromatic Systems. Synthesis of 5,6,8,9,10,11- Hexahydroindolo[2,1-a]isoquinolines
Efficient radical cyclization of alkyl iodides to various aromatic systems including pyrrole, indole, isoquinolone, pyridone, and benzene, mediated by dicumyl peroxide, is described. The methodology was used to provide access to 5,6,8,9,10,11-hexahydroindolo[2,1-a]isoquinoline derivatives.
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| Veröffentlicht in: | Journal of organic chemistry 2004-05, Vol.69 (11), p.4001-4004 |
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| container_end_page | 4004 |
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| container_issue | 11 |
| container_start_page | 4001 |
| container_title | Journal of organic chemistry |
| container_volume | 69 |
| creator | Menes-Arzate, Martha Martínez, Roberto Cruz-Almanza, Raymundo Muchowski, Joseph M Osornio, Yazmin M Miranda, Luis D |
| description | Efficient radical cyclization of alkyl iodides to various aromatic systems including pyrrole, indole, isoquinolone, pyridone, and benzene, mediated by dicumyl peroxide, is described. The methodology was used to provide access to 5,6,8,9,10,11-hexahydroindolo[2,1-a]isoquinoline derivatives. |
| doi_str_mv | 10.1021/jo0497048 |
| format | Article |
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| ispartof | Journal of organic chemistry, 2004-05, Vol.69 (11), p.4001-4004 |
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| language | eng |
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| source | American Chemical Society |
| subjects | Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with only one n hetero atom and condensed derivatives Organic chemistry Preparations and properties |
| title | Efficient, “Tin-Free” Radical Cyclization to Aromatic Systems. Synthesis of 5,6,8,9,10,11- Hexahydroindolo[2,1-a]isoquinolines |
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