Pediatric IgA nephropathies: clinical aspects and therapeutic approaches

The pediatric IgA nephropathies are IgA nephrothapy (Berger’s Disease) and Henoch-Schönlein purpura nephritis. Both conditions are reviewed in detail with respect to epidemiology, clinical features, outcome, prognostic markers, and therapeutic approaches. For both conditions variable disease severity and outcome along with the lack of conclusive evidence for efficacy of treatment based on randomized clinical trials makes it difficult to make strong recommendations regarding therapy.