Chiral Dimeric Capsules from N,C-Linked Peptidocalix[4]arenes Self-Assembled through an Antiparallel β-Sheetlike Motif

Chiral Dimeric Capsules from N,C-Linked Peptidocalix[4]arenes Self-Assembled through an Antiparallel β-Sheetlike Motif

The first example of a calix[4]arene amino acid is reported. It allowed the synthesis of the novel N,C-linked peptidocalix[4]arenes which self-assemble in low-polarity media to give chiral dimeric capsules held together by an antiparallel β-sheetlike hydrogen-bonding motif.

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Veröffentlicht in:Journal of the American Chemical Society 2004-05, Vol.126 (20), p.6204-6205
Hauptverfasser: Sansone, Francesco, Baldini, Laura, Casnati, Alessandro, Chierici, Elisa, Faimani, Giovanni, Ugozzoli, Franco, Ungaro, Rocco
Format: Artikel
Sprache:eng
Schlagworte:
Bridged-Ring Compounds - chemistry
Chemistry
Chloroform - chemistry
Exact sciences and technology
Magnetic Resonance Spectroscopy
Models, Molecular
Molecular Conformation
Noncondensed benzenic compounds
Organic chemistry
Phenols - chemistry
Preparations and properties
Solutions
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Zusammenfassung:The first example of a calix[4]arene amino acid is reported. It allowed the synthesis of the novel N,C-linked peptidocalix[4]arenes which self-assemble in low-polarity media to give chiral dimeric capsules held together by an antiparallel β-sheetlike hydrogen-bonding motif.
ISSN:0002-7863
1520-5126
DOI:10.1021/ja031511z