Receptors for bitter and sweet taste

The identification of two families of receptors, T1Rs and T2Rs, for sweet and bitter taste stimuli has opened the door to understanding some of the basic mechanisms underlying taste transduction in mammals. Studies of the functions of these receptors and their patterns of expression provide importan...

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Veröffentlicht in:	Current Opinion in Neurobiology 2002-08, Vol.12 (4), p.366-371
Hauptverfasser:	Montmayeur, Jean-Pierre, Matsunami, Hiroaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals bitter taste receptors genetics GPCRs Human Genome information Humans In Situ Hybridization molecular biology Receptors, Cell Surface - chemistry Receptors, Cell Surface - metabolism Receptors, G-Protein-Coupled sweet taste receptors Taste Taste Buds - anatomy & histology Taste Buds - chemistry Tongue - anatomy & histology umami taste receptors
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Beschreibung
Zusammenfassung:	The identification of two families of receptors, T1Rs and T2Rs, for sweet and bitter taste stimuli has opened the door to understanding some of the basic mechanisms underlying taste transduction in mammals. Studies of the functions of these receptors and their patterns of expression provide important information regarding the detection of structurally diverse taste compounds and the manner in which different taste qualities are encoded in the mouth. How how structurally different taste compounds detected and different taste qualities encoded in the mouth?
ISSN:	0959-4388 1873-6882
DOI:	10.1016/S0959-4388(02)00345-8