In vitro SAR of (5-(2 H)-isoxazolonyl) ureas, potent inhibitors of hormone-sensitive lipase

A series of (5-(2 H)-isoxazolonyl) ureas were developed as nanomolar inhibitors of hormone-sensitive lipase, an enzyme of potential importance in the treatment of diabetes. A series of (5-(2 H)-isoxazolonyl) ureas were developed as nanomolar inhibitors of hormone-sensitive lipase, an enzyme of poten...

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