Higher C-Reactive Protein Concentration and White Blood Cell Count in Subjects With More Coronary Risk Factors and/or Lower Physical Fitness Among Apparently Healthy Japanese

Of 2,722 people (1,876 men, mean age: 51.3±10.3 years; 846 women, mean age: 51.4±11.1) who underwent the fitness check program at Aichi Prefectural Center for Health Care, the concentration of C-reactive protein (CRP) and the white blood cell count (WBC) were investigated in relation to the number of coronary risk factors, maximum oxygen uptake (VO2max) quartiles and physical fitness score. CRP was measured by conventional latex immunoturbidimetric assay. Both CRP and WBC were higher in those who had more risk factors. In men the lowest mean CRP was 0.07 mg/dl in those with only one risk factor (RF1) and the highest was 0.29 mg/dl in RF6 (p