Clonogenic assay with established human tumour xenografts: correlation of in vitro to in vivo activity as a basis for anticancer drug discovery

Clonogenic assay with established human tumour xenografts: correlation of in vitro to in vivo activity as a basis for anticancer drug discovery

Pluripotent cells can be grown in clonogenic assays. The tumour stem-cell fraction, which accounts for

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Veröffentlicht in:European journal of cancer (1990) 2004-04, Vol.40 (6), p.802-820
Hauptverfasser: Fiebig, H.H, Maier, A, Burger, A.M
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antineoplastic Agents - therapeutic use
Cell Division
Chemosensitivity
Clonogenic assay
Drug Design
Drug discovery
Hematopoietic Stem Cells - drug effects
Humans
In Vitro Techniques
Mice
Mice, Nude
Neoplasm Metastasis - pathology
Neoplasm Transplantation
Neoplasms - drug therapy
Transplantation, Heterologous
Tumor Cells, Cultured
Tumor Stem Cell Assay - methods
Xenograft
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Zusammenfassung:Pluripotent cells can be grown in clonogenic assays. The tumour stem-cell fraction, which accounts for
ISSN:0959-8049
1879-0852
DOI:10.1016/j.ejca.2004.01.009