Coordination Chemistry of Fluorine in Fluorocarbons
Fluorine can do it. Not only oxygen but also fluorine, covalently bonded in organic molecules, is an important donor atom in the coordination chemistry of biorelevant metal ions such as Na+, K+, Mg2+ and Ca2+. Clear evidence in favour of such interactions will be presented in this Minireview, follow...
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Veröffentlicht in: | Chembiochem : a European journal of chemical biology 2004-05, Vol.5 (5), p.650-655 |
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creator | Plenio, Herbert |
description | Fluorine can do it. Not only oxygen but also fluorine, covalently bonded in organic molecules, is an important donor atom in the coordination chemistry of biorelevant metal ions such as Na+, K+, Mg2+ and Ca2+. Clear evidence in favour of such interactions will be presented in this Minireview, followed by a discussion of possible implications for fluorinated, bioactive compounds. |
doi_str_mv | 10.1002/cbic.200300752 |
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Not only oxygen but also fluorine, covalently bonded in organic molecules, is an important donor atom in the coordination chemistry of biorelevant metal ions such as Na+, K+, Mg2+ and Ca2+. Clear evidence in favour of such interactions will be presented in this Minireview, followed by a discussion of possible implications for fluorinated, bioactive compounds.</description><identifier>ISSN: 1439-4227</identifier><identifier>EISSN: 1439-7633</identifier><identifier>DOI: 10.1002/cbic.200300752</identifier><identifier>PMID: 15122637</identifier><language>eng</language><publisher>Weinheim: Wiley-VCH Verlag</publisher><subject>alkali metals ; alkaline earth metals ; coordination chemistry ; Crown Ethers - chemistry ; Crystallography, X-Ray ; fluorine ; Fluorine - chemistry ; fluorine-containing drugs ; Fluorocarbons - chemistry ; Hydrocarbons, Fluorinated - chemistry ; Ligands ; Magnetic Resonance Spectroscopy - methods ; Metals - chemistry ; Models, Molecular ; Molecular Structure</subject><ispartof>Chembiochem : a European journal of chemical biology, 2004-05, Vol.5 (5), p.650-655</ispartof><rights>Copyright © 2004 WILEY‐VCH Verlag GmbH & Co. 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Not only oxygen but also fluorine, covalently bonded in organic molecules, is an important donor atom in the coordination chemistry of biorelevant metal ions such as Na+, K+, Mg2+ and Ca2+. Clear evidence in favour of such interactions will be presented in this Minireview, followed by a discussion of possible implications for fluorinated, bioactive compounds.</description><subject>alkali metals</subject><subject>alkaline earth metals</subject><subject>coordination chemistry</subject><subject>Crown Ethers - chemistry</subject><subject>Crystallography, X-Ray</subject><subject>fluorine</subject><subject>Fluorine - chemistry</subject><subject>fluorine-containing drugs</subject><subject>Fluorocarbons - chemistry</subject><subject>Hydrocarbons, Fluorinated - chemistry</subject><subject>Ligands</subject><subject>Magnetic Resonance Spectroscopy - methods</subject><subject>Metals - chemistry</subject><subject>Models, Molecular</subject><subject>Molecular Structure</subject><issn>1439-4227</issn><issn>1439-7633</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEFPGzEQRq0KVCDttcc2p942jGd27fgIqwJBCFoVVImL5dhecNmswU4E-fcs2gi4cZo5vO_TzGPsG4cJB8B9Ow92ggAEICv8xHZ5SaqQgmhrs5eIcoft5fwfAJQg_pnt8IojCpK7jOoYkwudWYbYjetbvwh5mdbj2IyP2lVMofPj0A17tCbNY5e_sO3GtNl_3cwRuzr6dVmfFGcXx7P64KywpVBYTL0nFM6B5dxX5KkkL0qiZuoqS9hw7ywilaKpBDnq37FgnQJr1HyqHNKI_Rx671N8WPm81P1x1ret6XxcZS35VKGoqAcnA2hTzDn5Rt-nsDBprTnoF036RZN-1dQHvm-aV_OFd2_4xksPqAF4DK1ff1Cn68NZ_b68GLK9Sf_0mjXpTgtJstL_zo_1n9Prk0t5Dfp3z_8Y-MZEbW5SyPrqLwIn4KpELpGeAUjZi2I</recordid><startdate>20040503</startdate><enddate>20040503</enddate><creator>Plenio, Herbert</creator><general>Wiley-VCH Verlag</general><general>WILEY-VCH Verlag</general><general>WILEY‐VCH Verlag</general><scope>FBQ</scope><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040503</creationdate><title>Coordination Chemistry of Fluorine in Fluorocarbons</title><author>Plenio, Herbert</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4692-8ee326dd0c11e53e343e6433f8d5c32f1edc22346f563d3100c0cd90ca9b89d23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>alkali metals</topic><topic>alkaline earth metals</topic><topic>coordination chemistry</topic><topic>Crown Ethers - chemistry</topic><topic>Crystallography, X-Ray</topic><topic>fluorine</topic><topic>Fluorine - chemistry</topic><topic>fluorine-containing drugs</topic><topic>Fluorocarbons - chemistry</topic><topic>Hydrocarbons, Fluorinated - chemistry</topic><topic>Ligands</topic><topic>Magnetic Resonance Spectroscopy - methods</topic><topic>Metals - chemistry</topic><topic>Models, Molecular</topic><topic>Molecular Structure</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Plenio, Herbert</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Chembiochem : a European journal of chemical biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Plenio, Herbert</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Coordination Chemistry of Fluorine in Fluorocarbons</atitle><jtitle>Chembiochem : a European journal of chemical biology</jtitle><addtitle>ChemBioChem</addtitle><date>2004-05-03</date><risdate>2004</risdate><volume>5</volume><issue>5</issue><spage>650</spage><epage>655</epage><pages>650-655</pages><issn>1439-4227</issn><eissn>1439-7633</eissn><abstract>Fluorine can do it. Not only oxygen but also fluorine, covalently bonded in organic molecules, is an important donor atom in the coordination chemistry of biorelevant metal ions such as Na+, K+, Mg2+ and Ca2+. Clear evidence in favour of such interactions will be presented in this Minireview, followed by a discussion of possible implications for fluorinated, bioactive compounds.</abstract><cop>Weinheim</cop><pub>Wiley-VCH Verlag</pub><pmid>15122637</pmid><doi>10.1002/cbic.200300752</doi><tpages>6</tpages></addata></record> |
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subjects | alkali metals alkaline earth metals coordination chemistry Crown Ethers - chemistry Crystallography, X-Ray fluorine Fluorine - chemistry fluorine-containing drugs Fluorocarbons - chemistry Hydrocarbons, Fluorinated - chemistry Ligands Magnetic Resonance Spectroscopy - methods Metals - chemistry Models, Molecular Molecular Structure |
title | Coordination Chemistry of Fluorine in Fluorocarbons |
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