Suppressing the suppressors

Virologists have uncovered a novel viral mechanism that actively suppresses, rather than simply evades, host immunity. Surprisingly, the virus misappropriates a host protein that is generated by the immune system itself in response to infection.

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Bibliographische Detailangaben
Veröffentlicht in:	Drug discovery today 2004-05, Vol.9 (10), p.425-426
1. Verfasser:	Perks, Bea
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals dendritic cells (DCs) host immunity Immune Tolerance Interferon Type I - immunology lymphocytic choriomeningitis virus (LCMV) Lymphocytic choriomeningitis virus - immunology Rats T cells viral mechanism
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Virologists have uncovered a novel viral mechanism that actively suppresses, rather than simply evades, host immunity. Surprisingly, the virus misappropriates a host protein that is generated by the immune system itself in response to infection.
ISSN:	1359-6446 1878-5832
DOI:	10.1016/S1359-6446(04)03097-1