Are Criteria for Islet and Pancreas Donors Sufficiently Different to Minimize Competition?

Islet and pancreas transplantation may compete for a limited number of organs. We analyzed records from the national Swiss transplant registry during a 4‐year period to investigate the proportion of donors that are suitable for islet and pancreas transplantation. Suitability for pancreas transplanta...

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Veröffentlicht in:American journal of transplantation 2004-05, Vol.4 (5), p.763-766
Hauptverfasser: Ris, Frédéric, Toso, Christian, Veith, Florence Unno, Majno, Pietro, Morel, Philippe, Oberholzer, José
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Sprache:eng
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Zusammenfassung:Islet and pancreas transplantation may compete for a limited number of organs. We analyzed records from the national Swiss transplant registry during a 4‐year period to investigate the proportion of donors that are suitable for islet and pancreas transplantation. Suitability for pancreas transplantation was mainly defined as: age 10–45 years; weight ≤ 80 kg; BMI ≤ 25 kg/m2; amylasemia ≤ 150 U/l; ICU stay ≤ 3 days and absence of severe hypotension (MAP ≤ 60 mmHG). Between 1.1.1997 and 31.12.2000, data of 407 donors were collected, from which 321 donors were included in the study. Thirty‐three (10%), 143 (45%), and 23 (7%) donors fulfilled the criteria for pancreas, islet transplantation, and both procedures, respectively. Giving priority to pancreas transplantation and accepting the absence of one selection criterion, 90 (28%) pancreas and 100 (31%) islet donors were identified. We conclude that with current allocation policies prioritizing pancreas transplantation, pancreas and islet transplantation may coexist with little competition.
ISSN:1600-6135
1600-6143
DOI:10.1111/j.1600-6143.2004.00409.x