Forward Translocation Is the Natural Pathway of RNA Release at an Intrinsic Terminator

Intrinsic terminators of bacterial RNA polymerase are small (< ∼30 bp) sequences containing a dyad symmetry that encodes a hairpin in the RNA, followed immediately by a uridine-rich stretch of 5–9 nucleotides just before the site of RNA release. Formation of the RNA hairpin destabilizes the elong...

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Veröffentlicht in:	Molecular cell 2004-04, Vol.14 (1), p.117-126
Hauptverfasser:	Santangelo, Thomas J, Roberts, Jeffrey W
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - metabolism Base Sequence DNA - chemistry DNA - metabolism DNA-Directed RNA Polymerases - metabolism Molecular Sequence Data Nucleic Acid Conformation RNA, Bacterial - chemistry RNA, Bacterial - metabolism Terminator Regions, Genetic Transcription, Genetic
Online-Zugang:	Volltext
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