Terpenes from Juniperus przewalskii and their antitumor activities

Two new diterpenes were isolated from Juniperus przewalskii, together with 17 known terpense. Their structures were elucidated by spectroscopic methods (IR, MS, 1H, 13C and 2DNMR). In addition, 3 alpha-hinokiol (3) and 3 alpha-hydroxymannol (9) exhibited effective antitumor activities to cervical ca...

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Veröffentlicht in:	Pharmazie 2002-05, Vol.57 (5), p.343-345
Hauptverfasser:	WANG, Wen-Shu, LI, Er-Wei, JIA, Zhong-Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology Biological and medical sciences China Female General pharmacology HeLa Cells Humans Juniperus - chemistry Magnetic Resonance Spectroscopy Mass Spectrometry Medical sciences Optical Rotation Ovarian Neoplasms - drug therapy Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Spectrophotometry, Infrared Terpenes - isolation & purification Terpenes - pharmacology Tumor Cells, Cultured
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Zusammenfassung:	Two new diterpenes were isolated from Juniperus przewalskii, together with 17 known terpense. Their structures were elucidated by spectroscopic methods (IR, MS, 1H, 13C and 2DNMR). In addition, 3 alpha-hinokiol (3) and 3 alpha-hydroxymannol (9) exhibited effective antitumor activities to cervical carcinoma (HeLa) and human ovarian carcinoma (HO-8910) cell lines.
ISSN:	0031-7144