Graves' ophthalmopathy evolution studied by MRI during childhood and adolescence

Pediatric patients with Graves' disease (n = 26) were studied longitudinally by magnetic resonance imaging of the orbits, allowing an assessment of the enlargement of the extraocular muscles and orbital volume variations. The positive outcome of Graves' ophthalmopathy correlated with low T...

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Veröffentlicht in:The Journal of pediatrics 2004-04, Vol.144 (4), p.527-531
Hauptverfasser: Antoniazzi, Franco, Zamboni, Giorgio, Cerini, Roberto, Lauriola, Silvana, Dall'Agnola, Alberto, Tatò, Luciano
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container_end_page 531
container_issue 4
container_start_page 527
container_title The Journal of pediatrics
container_volume 144
creator Antoniazzi, Franco
Zamboni, Giorgio
Cerini, Roberto
Lauriola, Silvana
Dall'Agnola, Alberto
Tatò, Luciano
description Pediatric patients with Graves' disease (n = 26) were studied longitudinally by magnetic resonance imaging of the orbits, allowing an assessment of the enlargement of the extraocular muscles and orbital volume variations. The positive outcome of Graves' ophthalmopathy correlated with low TRAb (autoantibodies to thyroid-stimulating hormone receptor) titers at diagnosis and during follow-up and with prepubertal condition at diagnosis.
doi_str_mv 10.1016/j.jpeds.2004.01.033
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Adolescent
Biological and medical sciences
Child
Child, Preschool
Disease Progression
Endocrinopathies
Exophthalmos - pathology
Female
Graves Disease - pathology
Graves Disease - physiopathology
Humans
Longitudinal Studies
Magnetic Resonance Imaging
Male
Medical sciences
Non tumoral diseases. Target tissue resistance. Benign neoplasms
Oculomotor Muscles - growth & development
Oculomotor Muscles - pathology
Orbit - growth & development
Orbit - pathology
Puberty - physiology
Receptors, Thyrotropin - blood
Reference Values
Thyroid. Thyroid axis (diseases)
title Graves' ophthalmopathy evolution studied by MRI during childhood and adolescence
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