A Novel Enantioselective (2Z)-Alk-2-enylation of Aldehydes via an Allyl-Transfer Reaction from Chiral Allyl Donors Prepared from (+)-Isomenthone

A Novel Enantioselective (2Z)-Alk-2-enylation of Aldehydes via an Allyl-Transfer Reaction from Chiral Allyl Donors Prepared from (+)-Isomenthone

A highly enantioselective (2Z)-alk-2-enylation of aldehydes was successfully achieved by an allyl-transfer reaction from a chiral allyl donor, which was easily obtained by separation of a diastereomeric mixture of the corresponding homoallylic alcohol γ-adducts derived from (+)-isomenthone with alk-...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Organic letters 2004-04, Vol.6 (8), p.1261-1264
Hauptverfasser: Nokami, Junzo, Nomiyama, Kenta, Shafi, Siddiqi M, Kataoka, Kazuhide
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A highly enantioselective (2Z)-alk-2-enylation of aldehydes was successfully achieved by an allyl-transfer reaction from a chiral allyl donor, which was easily obtained by separation of a diastereomeric mixture of the corresponding homoallylic alcohol γ-adducts derived from (+)-isomenthone with alk-2-enylmagnesium chloride.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol0400140