South-East Asian ovalocytosis among the population of the Highlands of Madagascar: a vestige of the island's settlement
In the Madagascar Highlands, 0·76% of children from 168 random primary schools, and 19 of 150 families from 3 villages, had oval-shaped erythrocytes. Most harboured the deletion in the band 3 gene characteristic of South-East Asian ovalocytosis. This genetic trait supports the Indonesian origin of t...
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| Veröffentlicht in: | Transactions of the Royal Society of Tropical Medicine and Hygiene 2002-03, Vol.96 (2), p.143-144 |
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| container_title | Transactions of the Royal Society of Tropical Medicine and Hygiene |
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| creator | Rabe, T. Jambou, R. Rabarijaona, L. Raharimalala, L. Rason, M.A. Ariey, F. Dhermy, D. |
| description | In the Madagascar Highlands, 0·76% of children from 168 random primary schools, and 19 of 150 families from 3 villages, had oval-shaped erythrocytes. Most harboured the deletion in the band 3 gene characteristic of South-East Asian ovalocytosis. This genetic trait supports the Indonesian origin of the Madagascar settlement. |
| doi_str_mv | 10.1016/S0035-9203(02)90282-8 |
| format | Article |
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Hemoglobinopathies</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Cross-Sectional Studies</subject><subject>Diseases of red blood cells</subject><subject>Elliptocytosis, Hereditary - epidemiology</subject><subject>Elliptocytosis, Hereditary - genetics</subject><subject>Emigration and Immigration</subject><subject>erythrocytes</subject><subject>Gene Deletion</subject><subject>genetic traits</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Indonesia</subject><subject>Madagascar</subject><subject>Madagascar - epidemiology</subject><subject>Medical sciences</subject><subject>Mutation - genetics</subject><subject>Polymerase Chain Reaction - methods</subject><subject>Prevalence</subject><subject>schoolchildren</subject><subject>South-East Asian ovalocytosis</subject><subject>Tropical medicine</subject><issn>0035-9203</issn><issn>1878-3503</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF1v0zAUhi0EYt3gJ4Byw9eF4diOHWc3aKsGRRpC04qEuLFcx2kNSRxsp7B_T9KWTUhIXFk6el6_5zwIPSHwmgARb64BGMclBfYS6KsSqKRY3kMzIguJGQd2H81ukSN0HOM3AMoJLx-iI0KBcwlkhn5e-yFt8IWOKTuLTneZ3-rGm5vko4uZbn23ztLGZr3vh0Yn50ei3k0Wbr1pdFfFafBRV3qto9HhNNPZ1sbk1vYP6eLEvYhZtCk1trVdeoQe1LqJ9vHhPUGf310s5wt8-en9h_nZJTZ5XiacW6hWRUmFLMEIIiAnTJqqrjUwYSgUnBErpK5oofOCmroUNTGUFrYGWFHOTtDz_b998D-GcS3VumhsMy5k_RBVQSTQnJcjyPegCT7GYGvVB9fqcKMIqMm42hlXk04FVO2MKznmnh4KhlVrq7vUQfEIPDsAk56mDrozLt5xTHBWMhg52HN-6P_djf_qxlM33kdcTPbXbUiH70oUrOBq8eWrml-Rq-JcLNVy5N_ueTsa3zobVDTOdsZWLliTVOXdf679DQMjuiw</recordid><startdate>20020301</startdate><enddate>20020301</enddate><creator>Rabe, T.</creator><creator>Jambou, R.</creator><creator>Rabarijaona, L.</creator><creator>Raharimalala, L.</creator><creator>Rason, M.A.</creator><creator>Ariey, F.</creator><creator>Dhermy, D.</creator><general>Elsevier Ltd</general><general>Royal Society of Tropical Medicine and Hygiene</general><general>Elsevier</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20020301</creationdate><title>South-East Asian ovalocytosis among the population of the Highlands of Madagascar: a vestige of the island's settlement</title><author>Rabe, T. ; Jambou, R. ; Rabarijaona, L. ; Raharimalala, L. ; Rason, M.A. ; Ariey, F. ; Dhermy, D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c449t-4e0db7926890c61604138cdffa036c207531e68ad27a472cf96f1c227ef00b253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adult</topic><topic>adults</topic><topic>Altitude</topic><topic>Anemias. 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| ispartof | Transactions of the Royal Society of Tropical Medicine and Hygiene, 2002-03, Vol.96 (2), p.143-144 |
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| language | eng |
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| source | MEDLINE; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection |
| subjects | Adult adults Altitude Anemias. Hemoglobinopathies Biological and medical sciences Child Cross-Sectional Studies Diseases of red blood cells Elliptocytosis, Hereditary - epidemiology Elliptocytosis, Hereditary - genetics Emigration and Immigration erythrocytes Gene Deletion genetic traits Hematologic and hematopoietic diseases Humans Indonesia Madagascar Madagascar - epidemiology Medical sciences Mutation - genetics Polymerase Chain Reaction - methods Prevalence schoolchildren South-East Asian ovalocytosis Tropical medicine |
| title | South-East Asian ovalocytosis among the population of the Highlands of Madagascar: a vestige of the island's settlement |
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