Light-Directed Simultaneous Synthesis of Oligopeptides on Microarray Substrate Using a Photogenerated Acid

Photogenerated acid (PGA) was used as the acid to remove the protection group from amino acids or peptide oligomers. Comparative study of the deprotection using a PGA, trisarylsulfonium antimonyhexafluoride (SSb), and trifluoroacetic acid (TFA) was performed on glass microscope slides. The results s...

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Veröffentlicht in:	Biotechnology progress 2002, Vol.18 (3), p.641-646
Hauptverfasser:	Komolpis, Kittinan, Srivannavit, Onnop, Gulari, Erdogan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids - chemistry Animals Antimony - chemistry Biological and medical sciences Biotechnology Chemical industry. Chemical engineering Fundamental and applied biological sciences. Psychology Humans Industrial applications and implications. Economical aspects Mice Oligopeptides - chemical synthesis Photochemistry Spectrometry, Fluorescence Sulfonium Compounds - chemistry Trifluoroacetic Acid - chemistry
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