Severe fetal cytomegalovirus infection associated with cerebellar hemorrhage

Cytomegalovirus (CMV) is the most common cause of congenital infection worldwide. We report on a fatal fetal manifestation of primary maternal CMV infection including cerebellar hemorrhage and hydrops. The diagnosis was established by maternal serological tests, culture and polymerase chain reaction...

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Veröffentlicht in:	Ultrasound in obstetrics & gynecology 2004-04, Vol.23 (4), p.402-406
Hauptverfasser:	Ortiz, J. U., Ostermayer, E., Fischer, T., Kuschel, B., Rudelius, M., Schneider, K. T. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion, Incomplete Adult Biological and medical sciences Cerebellar Diseases - diagnosis Cerebellar Diseases - diagnostic imaging Cerebellar Diseases - virology cerebellar hemorrhage Cerebral Hemorrhage - diagnosis Cerebral Hemorrhage - diagnostic imaging Cerebral Hemorrhage - virology cytomegalovirus Cytomegalovirus Infections - diagnosis Cytomegalovirus Infections - diagnostic imaging Doppler velocimetry Fatal Outcome Female Fetal Diseases - diagnostic imaging Fetal Diseases - virology Gynecology. Andrology. Obstetrics Human cytomegalovirus Humans hydrops fetalis Medical sciences Pregnancy Pregnancy Complications, Infectious - diagnosis prenatal diagnosis Ultrasonography, Prenatal - methods
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Zusammenfassung:	Cytomegalovirus (CMV) is the most common cause of congenital infection worldwide. We report on a fatal fetal manifestation of primary maternal CMV infection including cerebellar hemorrhage and hydrops. The diagnosis was established by maternal serological tests, culture and polymerase chain reaction testing of amniotic fluid and fetal blood. The pregnancy was terminated. Postmortem examination confirmed the diagnosis. Copyright © 2004 ISUOG. Published by John Wiley & Sons, Ltd.
ISSN:	0960-7692 1469-0705
DOI:	10.1002/uog.1021