Phenanthridinium as an Artificial Base and Charge Donor in DNA

Phenanthridinium as an Artificial Base and Charge Donor in DNA

A tool for time‐resolved studies: The phenanthridinium unit of ethidium was incorporated into oligonucleotides (see scheme) as an artificial DNA base. The resulting duplexes can be used to study electron‐transfer processes by spectroscopic techniques and to compare the rates of reductive electron tr...

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Veröffentlicht in:Angewandte Chemie International Edition 2004-03, Vol.43 (14), p.1845-1847
Hauptverfasser: Amann, Nicole, Huber, Robert, Wagenknecht, Hans-Achim
Format: Artikel
Sprache:eng
Schlagworte:
DNA
DNA - chemical synthesis
DNA - chemistry
DNA - radiation effects
electron transfer
Ethidium - analogs & derivatives
Ethidium - chemistry
ethidium ion
fluorescence spectroscopy
Molecular Structure
oligonucleotides
Photochemistry
Temperature
Ultraviolet Rays
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Beschreibung
Zusammenfassung:A tool for time‐resolved studies: The phenanthridinium unit of ethidium was incorporated into oligonucleotides (see scheme) as an artificial DNA base. The resulting duplexes can be used to study electron‐transfer processes by spectroscopic techniques and to compare the rates of reductive electron transfer and oxidative hole transfer.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200353153