HDAC's at Work: Everyone Doing Their Part

The interplay between histone acetyltransferases (HATs) and histone deacetylases (HDACs) is key to the dynamics of chromatin structure and function. A recent report of genome-wide, microarray maps of histone acetylation has uncovered the intragenic targets for six different yeast HDACs and has led t...

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Veröffentlicht in:	Molecular Cell 2002-05, Vol.9 (5), p.921-922
1. Verfasser:	Peterson, Craig L
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Acetyltransferases - physiology Animals Chromatin - physiology Gene Expression Profiling Histone Acetyltransferases Histone Deacetylases - physiology Oligonucleotide Array Sequence Analysis Saccharomyces cerevisiae Proteins Structure-Activity Relationship Yeasts - enzymology
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Zusammenfassung:	The interplay between histone acetyltransferases (HATs) and histone deacetylases (HDACs) is key to the dynamics of chromatin structure and function. A recent report of genome-wide, microarray maps of histone acetylation has uncovered the intragenic targets for six different yeast HDACs and has led to the discovery of new heterochromatin-like domains.
ISSN:	1097-2765 1097-4164
DOI:	10.1016/S1097-2765(02)00534-8