Positive effects of anabolic steroids, vitamin D and calcium on muscle mass, bone mineral density and clinical function after a hip fracture: A randomised study of 63 women

A total of 63 women who had an operation for a fracture of the hip was randomly allocated to one year of treatment either with anabolic steroids, vitamin D and calcium (anabolic group) or with calcium only (control group). The thigh muscle volume was measured by quantitative CT. The bone mineral den...

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Veröffentlicht in:Journal of bone and joint surgery. British volume 2002-05, Vol.84 (4), p.497-503
Hauptverfasser: HEDSTRÖM, M, SJÖBERG, K, BROSJÖ, E, ASTRÖM, K, SJÖBERG, H, DALEN, N
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Sprache:eng
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Zusammenfassung:A total of 63 women who had an operation for a fracture of the hip was randomly allocated to one year of treatment either with anabolic steroids, vitamin D and calcium (anabolic group) or with calcium only (control group). The thigh muscle volume was measured by quantitative CT. The bone mineral density of the hip, femur and tibia was assessed by quantitative CT and dual-energy x-ray absorptiometry and of the heel by quantitative ultrasound. Quantitative CT showed that the anabolic group did not lose muscle volume during the first 12 months whereas the control group did (p
ISSN:0301-620X
2049-4394
2044-5377
2049-4408
DOI:10.1302/0301-620X.84B4.0840497