Periconicins, Two New Fusicoccane Diterpenes Produced by an Endophytic Fungus Periconia sp. with Antibacterial Activity

Two new fusicoccane diterpenes, named periconicins A (1) and B (2), with antibacterial activities have been isolated by bioassay-guided fractionation from an endophytic fungus Periconia sp., collected from small branches of Taxus cuspidata. The structures of the new compounds were determined by comb...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2004-03, Vol.67 (3), p.448-450
Hauptverfasser:	Kim, Sanghee, Shin, Dong-Sun, Lee, Taeho, Oh, Ki-Bong
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Antibiotics (antibacterial agents, antifungal agents) Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents Applied microbiology Bacteria - drug effects Biological and medical sciences Diterpenes - chemistry Diterpenes - isolation & purification Diterpenes - pharmacology Fundamental and applied biological sciences. Psychology Fungi - chemistry Korea Microbial Sensitivity Tests Microbiology Molecular Structure Nuclear Magnetic Resonance, Biomolecular Periconia Taxus Taxus cuspidata
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Zusammenfassung:	Two new fusicoccane diterpenes, named periconicins A (1) and B (2), with antibacterial activities have been isolated by bioassay-guided fractionation from an endophytic fungus Periconia sp., collected from small branches of Taxus cuspidata. The structures of the new compounds were determined by combined spectroscopic methods.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np030384h