Predictive factors of virological response to primary antiretroviral treatment

During 1999, first-line antiretroviral combinations for the treatment of HIV infections have diversified. The aim of our study was two-fold: define the factors associated with initial success and define the factors associated with virological rebound in patients in whom a primary antiretroviral ther...

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Veröffentlicht in:	La Presse médicale (1983) 2004-03, Vol.33 (5), p.310-315
Hauptverfasser:	Faucher, J-F, Challier, B, Chirouze, C, Drobacheff, C, Fischer, P, Lang, J-M, Boyer, L, May, T, Froidure, M, Chavanet, P, Lescure, F-X, Strady, C, Hoen, B
Format:	Artikel
Sprache:	fre
Schlagworte:	Adult Anti-HIV Agents - pharmacology Anti-HIV Agents - therapeutic use Antiretroviral Therapy, Highly Active CD4 Lymphocyte Count Cohort Studies Drug Evaluation Female France HIV Infections - drug therapy HIV Infections - virology HIV-1 - drug effects Human immunodeficiency virus Humans Male Middle Aged Retrospective Studies RNA, Viral - blood Viral Load Viremia - drug therapy Viremia - virology
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Zusammenfassung:	During 1999, first-line antiretroviral combinations for the treatment of HIV infections have diversified. The aim of our study was two-fold: define the factors associated with initial success and define the factors associated with virological rebound in patients in whom a primary antiretroviral therapy (ARV) had been initiated between 1999 and 2000. We conducted a retrospective multicenter study regrouping 6 HIV clinics in the North-East of France. Data were Issued from the patients medical files. Primary success was defined as plasma HIV RNA viral load (VL
ISSN:	0755-4982
DOI:	10.1016/S0755-4982(04)98570-3