Nonbenzamidine compounds as selective factor xa inhibitors

Nonbenzamidine compounds (imidazole, pyridine, pyrimidine, and thiazole derivatives) as selective serine protease factor Xa inhibitors are discussed.

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Bibliographische Detailangaben
Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2000-08, Vol.10 (15), p.1737-1739
Hauptverfasser:	He, Wei, Hanney, Barbara, Myers, Michael R, Spada, Alfred P, Brown, Karen, Colussi, Dennis, Chu, Valeria
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzamidines - chemistry Benzamidines - pharmacology Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Factor Xa Inhibitors Medical sciences Pharmacology. Drug treatments Serine Proteinase Inhibitors - chemistry Serine Proteinase Inhibitors - pharmacology Structure-Activity Relationship
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Beschreibung
Zusammenfassung:	Nonbenzamidine compounds (imidazole, pyridine, pyrimidine, and thiazole derivatives) as selective serine protease factor Xa inhibitors are discussed.
ISSN:	0960-894X 1464-3405
DOI:	10.1016/S0960-894X(00)00316-4