Relating biochemistry and function in the myosin superfamily

Relating biochemistry and function in the myosin superfamily

All characterized myosins share a common ATPase mechanism. However, detailed kinetic analyses suggest that modulation of the rate and equilibrium constants that define the ATPase cycle confers specific properties to these motor proteins, suiting them to specific physiological tasks. Understanding th...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Current opinion in cell biology 2004-02, Vol.16 (1), p.61-67
Hauptverfasser: De La Cruz, Enrique M, Ostap, E Michael
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Isoenzymes - chemistry
Isoenzymes - classification
Isoenzymes - metabolism
Kinetics
Myosin Heavy Chains - physiology
Myosins - chemistry
Myosins - classification
Myosins - metabolism
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:All characterized myosins share a common ATPase mechanism. However, detailed kinetic analyses suggest that modulation of the rate and equilibrium constants that define the ATPase cycle confers specific properties to these motor proteins, suiting them to specific physiological tasks. Understanding the kinetic mechanisms allows potential cellular functions of the different myosin classes and isoforms to be better defined.
ISSN:0955-0674
1879-0410
DOI:10.1016/j.ceb.2003.11.011