Activity-Responsive Pacing Produces Long-Term Heart Rate Variability

Introduction: Long‐term heart rate variability (HRV) measures, including the standard deviation of means of successive 5‐minute epochs of R‐R interval intervals (SDANN) and the power law slope (β), are important prognostic measures, yet their physiologic basis is unknown. We tested the hypothesis th...

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Veröffentlicht in:	Journal of cardiovascular electrophysiology 2004-02, Vol.15 (2), p.179-183
Hauptverfasser:	RAJ, SATISH R., ROACH, DANIEL E., KOSHMAN, MARY-LOU, SHELDON, ROBERT S.
Format:	Artikel
Sprache:	eng
Schlagworte:	activity Adult Aged autonomic nervous system Cardiac Pacing, Artificial Cross-Over Studies Electrocardiography, Ambulatory Female Heart Block - physiopathology Heart Block - therapy Heart Conduction System - pathology Heart Conduction System - surgery Heart Rate - physiology heart rate variability Humans Male Middle Aged Motor Activity - physiology Pacemaker, Artificial pacemakers Predictive Value of Tests prognosis Statistics as Topic Time Treatment Outcome
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Zusammenfassung:	Introduction: Long‐term heart rate variability (HRV) measures, including the standard deviation of means of successive 5‐minute epochs of R‐R interval intervals (SDANN) and the power law slope (β), are important prognostic measures, yet their physiologic basis is unknown. We tested the hypothesis that long‐term HRV arises from physical activity in a randomized cross‐over study in patients with rate‐responsive pacemakers. Methods and Results: Ten patients with complete heart block and dual‐chamber pacemakers underwent 24‐hour periods of ambulatory ECG in each of three pacing modes: atrially tracked, fixed‐rate, and rate‐responsive pacing. SDANN, ultralow frequency (ULF; frequencies
ISSN:	1045-3873 1540-8167
DOI:	10.1111/j.1540-8167.2004.03342.x