Disease progression in HIV-infected patients treated with stavudine vs. zidovudine

This prospective, observational study compared disease progression and death in HIV-1 patients treated with stavudine vs. zidovudine in the Collaborations in HIV Outcomes Research/U.S. (CHORUS) cohort. Patients with a first occurrence of CD4 count

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of clinical epidemiology 2004-01, Vol.57 (1), p.89-97
Hauptverfasser:	Justice, Amy C, Stein, Daniel S, Fusco, Gregory P, Sherrill, Beth H, Fusco, Jennifer S, Danehower, Susan C, Becker, Stephen L, Hansen, Nellie I, Graham, Neil M.H, the CHORUS Program Team
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Acquired Immunodeficiency Syndrome - diagnosis AIDS Anti-HIV Agents - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Antiretroviral agents Antiretroviral Therapy, Highly Active Antiviral agents Biological and medical sciences Chi-square test CHORUS Clinical outcomes Data collection Databases, Factual Disease prevention Disease Progression Disease-Free Survival Drug therapy Epidemiology Ethnicity Follow-Up Studies Health risks HIV HIV Infections - drug therapy HIV Infections - mortality HIV wasting HIV Wasting Syndrome - diagnosis Human immunodeficiency virus Human immunodeficiency virus 1 Human viral diseases Humans Infectious diseases Longitudinal study Medical sciences Mitochondrial DNA Mortality Observational studies Patients Pharmacology. Drug treatments Proportional Hazards Models Prospective Studies Reverse Transcriptase Inhibitors - therapeutic use Sensitivity analysis Stavudine Stavudine - therapeutic use Toxicity Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Zidovudine Zidovudine - therapeutic use
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Beschreibung
Zusammenfassung:	This prospective, observational study compared disease progression and death in HIV-1 patients treated with stavudine vs. zidovudine in the Collaborations in HIV Outcomes Research/U.S. (CHORUS) cohort. Patients with a first occurrence of CD4 count
ISSN:	0895-4356 1878-5921
DOI:	10.1016/S0895-4356(03)00245-2