Adiponectin is reduced in gestational diabetes mellitus in normal weight women

Background. Adiponectin is an adipose tissue‐derived protein counteracting insulin resistance and inflammation. We have compared women with gestational diabetes mellitus (GDM; n = 22) and normal pregnancies (controls; n = 29) to evaluate whether adiponectin represents a link between endocrine funct...

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Veröffentlicht in:	Acta obstetricia et gynecologica Scandinavica 2004-04, Vol.83 (4), p.341-347
Hauptverfasser:	Ranheim, Trine, Haugen, Fred, Staff, Anne Cathrine, Braekke, Kristin, Harsem, Nina K., Drevon, Christian A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin Adipose Tissue - metabolism Biological and medical sciences Body Mass Index Body Weight Case-Control Studies Diabetes, Gestational - metabolism Female gestational diabetes mellitus Glucose Tolerance Test Gynecology. Andrology. Obstetrics Humans Insulin Resistance - physiology Intercellular Signaling Peptides and Proteins Medical sciences Metabolic diseases Obesity Pregnancy Proteins - metabolism RNA, Messenger - metabolism
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Zusammenfassung:	Background. Adiponectin is an adipose tissue‐derived protein counteracting insulin resistance and inflammation. We have compared women with gestational diabetes mellitus (GDM; n = 22) and normal pregnancies (controls; n = 29) to evaluate whether adiponectin represents a link between endocrine function of adipose tissue and the development of diabetes during pregnancy. Methods. The participants were categorized according to their prepregnancy body mass index (BMI) into two classes: BMI
ISSN:	0001-6349 1600-0412
DOI:	10.1111/j.0001-6349.2004.00413.x