Sex Differences in Outcomes After Cardiac Catheterization: Effect Modification by Treatment Strategy and Time

CONTEXT Studies comparing outcomes of cardiac care in women vs men yield various results, with some suggesting worse outcomes for women and others suggesting equivalent outcomes. OBJECTIVE To determine whether extent of coronary disease, treatment strategy, and follow-up time influence the risk of d...

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Veröffentlicht in:JAMA : the journal of the American Medical Association 2004-03, Vol.291 (10), p.1220-1225
Hauptverfasser: King, Kathryn M, Ghali, William A, Faris, Peter D, Curtis, Michael J, Galbraith, P. Diane, Graham, Michelle M, Knudtson, Merril L
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Sprache:eng
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Zusammenfassung:CONTEXT Studies comparing outcomes of cardiac care in women vs men yield various results, with some suggesting worse outcomes for women and others suggesting equivalent outcomes. OBJECTIVE To determine whether extent of coronary disease, treatment strategy, and follow-up time influence the risk of death in women vs men among patients who have had cardiac catheterization. DESIGN, SETTING, AND PATIENTS We studied a large inception cohort by using detailed clinical data from a registry of 37 401 patients undergoing cardiac catheterization in Alberta, Canada, from 1995-2000, with follow-up through December 31, 2001. MAIN OUTCOME MEASURES The risk of death for women vs men was assessed for all patients combined and then in analyses stratified by degree of coronary anatomic risk and by treatment strategy (no revascularization, percutaneous coronary intervention [PCI], coronary artery bypass graft [CABG] surgery). The latter analysis included a graphic assessment of the changing relative risk over time for women vs men. RESULTS Women had higher 1-year mortality than men did (5.6% vs 4.6%; P
ISSN:0098-7484
1538-3598
DOI:10.1001/jama.291.10.1220