Maternal haemolysis, elevated liver enzymes and low platelets syndrome: Perinatal and neurodevelopmental neonatal outcomes for infants weighing less than 1250 g

Objectives: To study mortality and short‐term morbidity of infants born to women with HELLP (haemolysis, elevated liver enzymes, and low platelets) syndrome and to compare the long‐term neurodevelopmental morbidity of a subgroup with birth weight (BWT) less than 1250 g (study group) with weight matched controls. Methods: Retrospective chart review and prospective neurodevelopmental follow‐up through a Perinatal Follow‐up clinic. Analysis of perinatal and neonatal data for women diagnosed with HELLP from 1993 to 1996. Neurodevelopmental outcome for the study group was compared to a group of weight matched controls. Results: A total of 109 infants (mean gestational age 32.6 weeks, mean BWT 1766 g) were born to 104 women with HELLP syndrome. There was a significant decrease in mortality (P = 0.002) and morbidity (P